When the old-old-old-fashioned vampire Vlad arrives at the hotel for an impromptu family get-together, Hotel Transylvania is in for a collision of supernatural old-school and modern day cool.

After the disastrous food storm in the first film, Flint and his friends are forced to leave the town. Flint accepts the invitation from his idol Chester V to join The Live Corp Company, which has been tasked to clean the island, and where the best inventors in the world create technologies for the betterment of mankind. When Flint discovers that his machine still operates and now creates mutant food beasts like living pickles, hungry tacodiles, shrimpanzees and apple pie-thons, he and his friends must return to save the world.

Welcome to Hotel Transylvania, Dracula's lavish five-stake resort, where monsters and their families can live it up and no humans are allowed. One special weekend, Dracula has invited all his best friends to celebrate his beloved daughter Mavis's 118th birthday. For Dracula catering to all of these legendary monsters is no problem but the party really starts when one ordinary guy stumbles into the hotel and changes everything!

While in his teens, Donny fathered a son, Todd, and raised him as a single parent up until Todd's 18th birthday. Now, after not seeing each other for years, Todd's world comes crashing down when Donny resurfaces just before Todd's wedding.

Dylan and Jamie think it's going to be easy to add the simple act of sex to their friendship, despite what Hollywood romantic comedies would have them believe. They soon discover however that getting physical really does always lead to complications.