Follows 20-year-old Drea, who reluctantly takes a job babysitting for a professor of a college she hopes to attend. Struggling to entertain the professor's children Trissy and Jake, along with her own little brother Phillip , Drea takes them on a hike, unaware that mysterious alien critters have crash-landed and started devouring every living thing they encounter.

Intergalactic warrior Star Butterfly arrives on Earth to live with the Diaz family. She continues to battle villains throughout the universe and high school, mainly to protect her extremely powerful wand, an object that still confuses her.