An emotional thrill ride through the day-to-day chaos of the city's most explosive hospital and the courageous team of doctors who hold it together. They will tackle unique new cases inspired by topical events, forging fiery relationships in the pulse-pounding pandemonium of the emergency room.

An edge-of-your-seat view into the lives of everyday heroes committed to one of America's noblest professions. For the firefighters, rescue squad and paramedics of Chicago Firehouse 51, no occupation is more stressful or dangerous, yet so rewarding and exhilarating. These courageous men and women are among the elite who forge headfirst into danger when everyone else is running the other way and whose actions make the difference between life and death.

The series follows Carrie, Miranda, and Charlotte as they navigate the journey from the complicated reality of life and friendship in their 30s to the even more complicated reality of life and friendship in their 50s.

Carrie, Charlotte, and Miranda are all married now, but they're still up for a little fun in the sun. When Samantha gets the chance to visit one of the most extravagant vacation destinations on the planet and offers to bring them all along, they surmise that a women-only retreat may be the perfect excuse to eschew their responsibilities and remember what life was like before they decided to settle down.