A young woman is held captive in an underground medical facility where selected individuals are perpetually mutilated and then healed using an experimental miracle drug: a panacea.

Friends gather at a wedding, but the celebration's shattered by terrifying apocalyptic events, which force them to re-examine life, choices they've made...

Framed for crimes against the country, the G.I. Joe team is terminated by Presidential order. This forces the G.I. Joes into not only fighting their mortal enemy Cobra; they are forced to contend with threats from within the government that jeopardize their very existence.