James and Sade adjust to being together 24/7 in quarantine. Nanda spends time with her husband, in a nursing home. Oscar and Elle try online dating. Sophie returns home from college to her parents, who have decided to separate.

When Elliot, a brash 23-year-old living carefree in New York City, meets the sensible Mia and receives a damning diagnosis all in the same week, his world is turned completely upside down. But as their love blossoms amidst the chaos of his treatment, they discover that Elliot's illness is not the real test of their relationship – it's everything else.

The supernatural phenomenon begins again with a fresh crop of inspiring heroes who take on the ultimate struggle between those with extraordinary abilities and those with nefarious motives to hunt and harness their powers. Epic adventures await these newly empowered allies as they cross paths with some of the original characters, unlocking the mysterious fate of the universe and their place within it.